Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling

In response to extracellular signals, many signalling proteins associated with the plasma membrane are sorted into endosomes. This involves endosomal fusion, which depends on the complexes HOPS and CORVET. Whether and how their subunits themselves modulate signal transduction is unknown. We show tha...

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Detalles Bibliográficos
Autores principales: Segala, Gregory, Bennesch, Marcela A., Ghahhari, Nastaran Mohammadi, Pandey, Deo Prakash, Echeverria, Pablo C., Karch, François, Maeda, Robert K., Picard, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478910/
https://www.ncbi.nlm.nih.gov/pubmed/31015428
http://dx.doi.org/10.1038/s41467-019-09800-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478910/
https://www.ncbi.nlm.nih.gov/pubmed/31015428
http://dx.doi.org/10.1038/s41467-019-09800-y

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