Excessive miR-25-3p maturation via N(6)-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression

N(6)-methyladenosine (m(6)A) modification is an important mechanism in miRNA processing and maturation, but the role of its aberrant regulation in human diseases remained unclear. Here, we demonstrate that oncogenic primary microRNA-25 (miR-25) in pancreatic duct epithelial cells can be excessively...

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Detalles Bibliográficos
Autores principales: Zhang, Jialiang, Bai, Ruihong, Li, Mei, Ye, Huilin, Wu, Chen, Wang, Chengfeng, Li, Shengping, Tan, Liping, Mai, Dongmei, Li, Guolin, Pan, Ling, Zheng, Yanfen, Su, Jiachun, Ye, Ying, Fu, Zhiqiang, Zheng, Shangyou, Zuo, Zhixiang, Liu, Zexian, Zhao, Qi, Che, Xu, Xie, Dan, Jia, Weihua, Zeng, Mu-Sheng, Tan, Wen, Chen, Rufu, Xu, Rui-Hua, Zheng, Jian, Lin, Dongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478927/
https://www.ncbi.nlm.nih.gov/pubmed/31015415
http://dx.doi.org/10.1038/s41467-019-09712-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478927/
https://www.ncbi.nlm.nih.gov/pubmed/31015415
http://dx.doi.org/10.1038/s41467-019-09712-x

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