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The Na(+/)H(+)-Exchanger NHE1 Regulates Extra- and Intracellular pH and Nimodipine-sensitive [Ca(2+)](i) in the Suprachiasmatic Nucleus

The central clock in the suprachiasmatic nucleus (SCN) has higher metabolic activity than extra-SCN areas in the anterior hypothalamus. Here we investigated whether the Na(+)/H(+) exchanger (NHE) may regulate extracellular pH (pHe), intracellular pH (pHi) and [Ca(2+)](i) in the SCN. In hypothalamic...

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Detalles Bibliográficos
Autores principales: Cheng, Pi-Cheng, Lin, Hsin-Yi, Chen, Ya-Shuan, Cheng, Ruo-Ciao, Su, Hung-Che, Huang, Rong-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478949/
https://www.ncbi.nlm.nih.gov/pubmed/31015514
http://dx.doi.org/10.1038/s41598-019-42872-w