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Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis

In Mycobacterium tuberculosis, recent genome-wide association studies have identified a novel constellation of mutations that are correlated with high-level drug resistances. Interpreting the functional importance of the new resistance-associated mutations has been complicated, however, by a lack of...

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Detalles Bibliográficos
Autores principales: Hicks, Nathan D., Carey, Allison F., Yang, Jian, Zhao, Yanlin, Fortune, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479004/
https://www.ncbi.nlm.nih.gov/pubmed/31015328
http://dx.doi.org/10.1128/mBio.00616-19