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A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Infections with parasitic nematodes are among the most significant of the neglected tropical diseases affecting about a billion people living mainly in tropical regions with low economic activity. The most effective current strategy to control nematode infections involves large scale treatment progr...

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Detalles Bibliográficos
Autores principales: Pandarakalam, George Cherian, Speake, Michael, McElroy, Stuart, Alturkistani, Ammar, Philippe, Lucas, Pettitt, Jonathan, Müller, Berndt, Connolly, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479105/
https://www.ncbi.nlm.nih.gov/pubmed/31015150
http://dx.doi.org/10.1016/j.ijpddr.2019.04.001