Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos

Angiogenesis is a crucial event for tumor progression and metastasis. It is the process through which new blood vessels are formed and has become a therapeutic target in many cancer therapies. However, current anti-angiogenic drugs such as Thalidomide still have detrimental teratogenic effects. This...

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Detalles Bibliográficos
Autores principales: Mercurio, Annalisa, Sharples, Lucy, Corbo, Filomena, Franchini, Carlo, Vacca, Angelo, Catalano, Alessia, Carocci, Alessia, Kamm, Roger D., Pavesi, Andrea, Adriani, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479179/
https://www.ncbi.nlm.nih.gov/pubmed/31057399
http://dx.doi.org/10.3389/fphar.2019.00349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479179/
https://www.ncbi.nlm.nih.gov/pubmed/31057399
http://dx.doi.org/10.3389/fphar.2019.00349

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