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Electrophysiological and Pharmacological Characterization of Human Inwardly Rectifying K(ir)2.1 Channels on an Automated Patch-Clamp Platform

Inwardly rectifying I(K1) potassium currents of the heart control the resting membrane potential of ventricular cardiomyocytes during diastole and contribute to their repolarization after each action potential. Mutations in the gene encoding K(ir)2.1 channels, which primarily conduct ventricular I(K...

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Detalles Bibliográficos
Autores principales: Sanson, Camille, Schombert, Brigitte, Filoche-Rommé, Bruno, Partiseti, Michel, Bohme, G. Andrees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479253/
https://www.ncbi.nlm.nih.gov/pubmed/30835490
http://dx.doi.org/10.1089/adt.2018.882