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Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors

Recent studies have demonstrated that human neutrophil elastase (HNE) can be used as marker for inflammation/infection of chronic wounds since it was found to be present in high concentration in exudate collected from chronic wounds. Biosensors used in wound care benefit from a chromogenic signallin...

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Detalles Bibliográficos
Autores principales: Ferreira, Ana V., Antunes, Egipto, Ribeiro, Artur, Matamá, Teresa, Azoia, Nuno G., Cunha, Joana, Cavaco-Paulo, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479270/
https://www.ncbi.nlm.nih.gov/pubmed/31049301
http://dx.doi.org/10.1016/j.btre.2019.e00324