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Structural and Computational Characterization of Disease-Related Mutations Involved in Protein-Protein Interfaces

One of the known potential effects of disease-causing amino acid substitutions in proteins is to modulate protein-protein interactions (PPIs). To interpret such variants at the molecular level and to obtain useful information for prediction purposes, it is important to determine whether they are loc...

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Detalles Bibliográficos
Autores principales: Navío, Dàmaris, Rosell, Mireia, Aguirre, Josu, de la Cruz, Xavier, Fernández-Recio, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479360/
https://www.ncbi.nlm.nih.gov/pubmed/30934865
http://dx.doi.org/10.3390/ijms20071583