A Single Mutation Increases the Thermostability and Activity of Aspergillus terreus Amine Transaminase

Enhancing the thermostability of (R)-selective amine transaminases (AT-ATA) will expand its application in the asymmetric synthesis of chiral amines. In this study, mutual information and coevolution networks of ATAs were analyzed by the Mutual Information Server to Infer Coevolution (MISTIC). Subse...

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Detalles Bibliográficos
Autores principales: Zhu, Wan-Li, Hu, Sheng, Lv, Chang-Jiang, Zhao, Wei-Rui, Wang, Hong-Peng, Mei, Jia-Qi, Mei, Le-He, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479498/
https://www.ncbi.nlm.nih.gov/pubmed/30934681
http://dx.doi.org/10.3390/molecules24071194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479498/
https://www.ncbi.nlm.nih.gov/pubmed/30934681
http://dx.doi.org/10.3390/molecules24071194

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