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A Single Mutation Increases the Thermostability and Activity of Aspergillus terreus Amine Transaminase
Enhancing the thermostability of (R)-selective amine transaminases (AT-ATA) will expand its application in the asymmetric synthesis of chiral amines. In this study, mutual information and coevolution networks of ATAs were analyzed by the Mutual Information Server to Infer Coevolution (MISTIC). Subse...
Autores principales: | Zhu, Wan-Li, Hu, Sheng, Lv, Chang-Jiang, Zhao, Wei-Rui, Wang, Hong-Peng, Mei, Jia-Qi, Mei, Le-He, Huang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479498/ https://www.ncbi.nlm.nih.gov/pubmed/30934681 http://dx.doi.org/10.3390/molecules24071194 |
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