Development and Palatability Assessment of Norvir(®) (Ritonavir) 100 mg Powder for Pediatric Population

Norvir(®) (ritonavir) is a Biopharmaceutical Classification System Class IV compound with poor solubility in water (~5 µg/mL) and limited oral bioavailability. Early stage development efforts were focused on an oral solution (OS) which provided reasonable bioavailability but exhibited taste-masking...

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Detalles Bibliográficos
Autores principales: Morris, John B., Tisi, David A., Tan, David Cheng Thiam, Worthington, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479559/
https://www.ncbi.nlm.nih.gov/pubmed/30959935
http://dx.doi.org/10.3390/ijms20071718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479559/
https://www.ncbi.nlm.nih.gov/pubmed/30959935
http://dx.doi.org/10.3390/ijms20071718

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