Lack of Cathepsin D in the Renal Proximal Tubular Cells Resulted in Increased Sensitivity against Renal Ischemia/Reperfusion Injury

Cathepsin D is one of the major lysosomal aspartic proteases that is essential for the normal functioning of the autophagy-lysosomal system. In the kidney, cathepsin D is enriched in renal proximal tubular epithelial cells, and its levels increase during acute kidney injury. To investigate how cathe...

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Detalles Bibliográficos
Autores principales: Suzuki, Chigure, Tanida, Isei, Ohmuraya, Masaki, Oliva Trejo, Juan Alejandro, Kakuta, Soichiro, Sunabori, Takehiko, Uchiyama, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479628/
https://www.ncbi.nlm.nih.gov/pubmed/30959855
http://dx.doi.org/10.3390/ijms20071711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479628/
https://www.ncbi.nlm.nih.gov/pubmed/30959855
http://dx.doi.org/10.3390/ijms20071711

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