In Vitro and In Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2

Protein kinase CK2 is an emerging target for therapeutic intervention in human diseases, particularly in cancer. Inhibitors of this enzyme are currently in clinical trials, indicating the druggability of human CK2. By virtual screening of the ZINC database, we found that the natural compound bikaver...

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Detalles Bibliográficos
Autores principales: Haidar, Samer, Aichele, Dagmar, Birus, Robin, Hielscher, Janine, Laitinen, Tuomo, Poso, Antti, Jose, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479664/
https://www.ncbi.nlm.nih.gov/pubmed/30965682
http://dx.doi.org/10.3390/molecules24071380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479664/
https://www.ncbi.nlm.nih.gov/pubmed/30965682
http://dx.doi.org/10.3390/molecules24071380

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