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A role for foregut tyrosine metabolism in glucose tolerance

OBJECTIVE: We hypothesized that DA and L-DOPA derived from nutritional tyrosine and the resultant observed postprandial plasma excursions of L-DOPA and DA might affect glucose tolerance via their ability to be taken-up by beta cells and inhibit glucose-stimulated β-cell insulin secretion. METHODS: T...

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Detalles Bibliográficos
Autores principales: Korner, Judith, Cline, Gary W., Slifstein, Mark, Barba, Pasquale, Rayat, Gina R., Febres, Gerardo, Leibel, Rudolph L., Maffei, Antonella, Harris, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479665/
https://www.ncbi.nlm.nih.gov/pubmed/30876866
http://dx.doi.org/10.1016/j.molmet.2019.02.008