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Changes in the Expression of Aquaporin-3 in the Gastrointestinal Tract Affect Drug Absorption

Aquaporin-3 (AQP3) plays an important role in water transport in the gastrointestinal (GI) tract. In this study, we conducted a Caco-2 cell permeability assay to examine how changes in the expression and function of AQP3 affect the rate at which a drug is absorbed via passive transport in the GI tra...

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Detalles Bibliográficos
Autores principales: Ikarashi, Nobutomo, Nagoya, Chika, Kon, Risako, Kitaoka, Satoshi, Kajiwara, Sayuri, Saito, Masayo, Kawabata, Akane, Ochiai, Wataru, Sugiyama, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479729/
https://www.ncbi.nlm.nih.gov/pubmed/30925715
http://dx.doi.org/10.3390/ijms20071559