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Phage-Assisted Evolution of Bacillus methanolicus Methanol Dehydrogenase 2

[Image: see text] Synthetic methylotrophy, the modification of organisms such as E. coli to grow on methanol, is a longstanding goal of metabolic engineering and synthetic biology. The poor kinetic properties of NAD-dependent methanol dehydrogenase, the first enzyme in most methanol assimilation pat...

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Detalles Bibliográficos
Autores principales: Roth, Timothy B., Woolston, Benjamin M., Stephanopoulos, Gregory, Liu, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479731/
https://www.ncbi.nlm.nih.gov/pubmed/30856338
http://dx.doi.org/10.1021/acssynbio.8b00481