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Structural Determinants of Substrate Specificity of Omega-3 Desaturases from Mortierella alpina and Rhizophagus irregularis by Domain-Swapping and Molecular Docking

Although various ω-3 fatty acid desaturases (ω3Des) have been identified and well-studied regarding substrate preference and regiospecificity, the molecular mechanism of their substrate specificities remains to be investigated. Here we compared two ω3Des, FADS15 from Mortierella alpina and oRiFADS17...

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Detalles Bibliográficos
Autores principales: Rong, Chunchi, Chen, Haiqin, Tang, Xin, Gu, Zhennan, Zhao, Jianxin, Zhang, Hao, Chen, Yongquan, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479736/
https://www.ncbi.nlm.nih.gov/pubmed/30935072
http://dx.doi.org/10.3390/ijms20071603