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Proinsulin C-Peptide Enhances Cell Survival and Protects against Simvastatin-Induced Myotoxicity in L6 Rat Myoblasts

The repair capacity of progenitor skeletal muscle satellite cells (SC) in Type 1 diabetes mellitus (T1DM) is decreased. This is associated with the loss of skeletal muscle function. In T1DM, the deficiency of C-peptide along with insulin is associated with an impairment of skeletal muscle functions...

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Detalles Bibliográficos
Autores principales: Essid, Sumia Mohamed, Bevington, Alan, Brunskill, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479794/
https://www.ncbi.nlm.nih.gov/pubmed/30987105
http://dx.doi.org/10.3390/ijms20071654