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Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity

Kallikrein 13 (KLK13) was first identified as an enzyme that is downregulated in a subset of breast tumors. This serine protease has since been implicated in a number of pathological processes including ovarian, lung and gastric cancers. Here we report the design, synthesis and deconvolution of libr...

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Detalles Bibliográficos
Autores principales: Gruba, Natalia, Bielecka, Ewa, Wysocka, Magdalena, Wojtysiak, Anna, Brzezińska-Bodal, Magdalena, Sychowska, Kamila, Kalińska, Magdalena, Magoch, Małgorzata, Pęcak, Aleksandra, Falkowski, Katherine, Wiśniewska, Magdalena, Sąsiadek, Laura, Płaza, Karolina, Kroll, Eileen, Pejkovska, Anastasija, Rehders, Maren, Brix, Klaudia, Dubin, Grzegorz, Kantyka, Tomasz, Potempa, Jan, Lesner, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479877/
https://www.ncbi.nlm.nih.gov/pubmed/30925705
http://dx.doi.org/10.3390/ijms20071557