Activation of PPARs Modulates Signalling Pathways and Expression of Regulatory Genes in Osteoclasts Derived from Human CD14+ Monocytes

Osteoclasts are the sole bone resorbing cell in the body and their over activity is key in the development of osteoporosis. Osteoclastogenesis is mediated by receptor activator of nuclear factor κB ligand (RANKL) signalling pathways. Unsaturated fatty acids (UFA) are known to inhibit osteoclastogene...

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Detalles Bibliográficos
Autores principales: Kasonga, Abe, Kruger, Marlena C., Coetzee, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479901/
https://www.ncbi.nlm.nih.gov/pubmed/30979019
http://dx.doi.org/10.3390/ijms20071798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479901/
https://www.ncbi.nlm.nih.gov/pubmed/30979019
http://dx.doi.org/10.3390/ijms20071798

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