Synthesis and Antiproliferative Activities of Conjugates of Paclitaxel and Camptothecin with a Cyclic Cell-Penetrating Peptide

Cell-penetrating peptide [WR](5) has been previously shown to be an efficient molecular transporter for various hydrophilic and hydrophobic molecules. The peptide was synthesized using Fmoc/tBu solid-phase chemistry, and one arginine was replaced with one lysine to enable the conjugation with the an...

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Detalles Bibliográficos
Autores principales: El-Sayed, Naglaa Salem, Shirazi, Amir Nasrolahi, Sajid, Muhammad Imran, Park, Shang Eun, Parang, Keykavous, Tiwari, Rakesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480016/
https://www.ncbi.nlm.nih.gov/pubmed/30978971
http://dx.doi.org/10.3390/molecules24071427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480016/
https://www.ncbi.nlm.nih.gov/pubmed/30978971
http://dx.doi.org/10.3390/molecules24071427

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