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Metabotropic Glutamate Receptor 5 and 8 Modulate the Ameliorative Effect of Ultramicronized Palmitoylethanolamide on Cognitive Decline Associated with Neuropathic Pain

This study investigated whether metabotropic glutamate receptor (mGluR) 5 and 8 are involved in the effect of ultramicronizedpalmitoylethanolamide (um-PEA) on the cognitive behavior and long term potentiation (LTP) at entorhinal cortex (LEC)-dentate gyrus (DG) pathway in mice rendered neuropathic by...

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Detalles Bibliográficos
Autores principales: Boccella, Serena, Marabese, Ida, Iannotta, Monica, Belardo, Carmela, Neugebauer, Volker, Mazzitelli, Mariacristina, Pieretti, Gorizio, Maione, Sabatino, Palazzo, Enza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480075/
https://www.ncbi.nlm.nih.gov/pubmed/30970677
http://dx.doi.org/10.3390/ijms20071757