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Circulating miRNA Signature as a Potential Biomarker for the Prediction of Analgesic Efficacy of Hydromorphone

No practical biomarkers currently exist for the prediction of the analgesic efficacy of opioids. Previously, we reported circulating miRNA signatures differentially regulated by µ-opioid receptor (MOR) agonists in healthy subjects. We hypothesized that these miRNAs could be potential pharmacodynamic...

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Detalles Bibliográficos
Autores principales: Kiyosawa, Naoki, Watanabe, Kenji, Toyama, Kaoru, Ishizuka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480077/
https://www.ncbi.nlm.nih.gov/pubmed/30987164
http://dx.doi.org/10.3390/ijms20071665