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Discovery of Novel Triazole-Containing Pyrazole Ester Derivatives as Potential Antibacterial Agents

To develop new antibacterial agents, a series of novel triazole-containing pyrazole ester derivatives were designed and synthesized and their biological activities were evaluated as potential topoisomerase II inhibitors. Compound 4d exhibited the most potent antibacterial activity with Minimum inhib...

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Detalles Bibliográficos
Autores principales: Chu, Ming-Jie, Wang, Wei, Ren, Zi-Li, Liu, Hao, Cheng, Xiang, Mo, Kai, Wang, Li, Tang, Feng, Lv, Xian-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480153/
https://www.ncbi.nlm.nih.gov/pubmed/30987179
http://dx.doi.org/10.3390/molecules24071311