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The Asymmetric A(3)(Aldehyde–Alkyne–Amine) Coupling: Highly Enantioselective Access to Propargylamines

The recent developments in asymmetric A(3) (aldehyde–alkyne–amine) coupling has been summarized in this review. Several interesting modifications of the ligands enabled the highly enantioselective synthesis of chiral propargylamines, which are further used in the construction of nitrogen-containing...

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Detalles Bibliográficos
Autores principales: Mo, Jia-Nan, Su, Junqi, Zhao, Jiannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480255/
https://www.ncbi.nlm.nih.gov/pubmed/30925732
http://dx.doi.org/10.3390/molecules24071216