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Genetic Restoration of Heme Oxygenase-1 Expression Protects from Type 1 Diabetes in NOD Mice

Antigen-presenting cells (APCs) including dendritic cells (DCs) play a critical role in the development of autoimmune diseases by presenting self-antigen to T-cells. Different signals modulate the ability of APCs to activate or tolerize autoreactive T-cells. Since the expression of heme oxygenase-1...

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Detalles Bibliográficos
Autores principales: Pogu, Julien, Tzima, Sotiria, Kollias, Georges, Anegon, Ignacio, Blancou, Philippe, Simon, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480274/
https://www.ncbi.nlm.nih.gov/pubmed/30987262
http://dx.doi.org/10.3390/ijms20071676