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The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation

OBJECTIVE: The mixed lineage kinase domain like (MLKL) protein, receptor interacting protein (RIPK) 1, and RIPK3 are key regulators of necroptosis, a highly pro-inflammatory mode of cell death that has been implicated in various pathological processes and human diseases. However, the role of these n...

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Detalles Bibliográficos
Autores principales: Xu, Haixia, Du, Xiao, Liu, Geng, Huang, Shuang, Du, Wenya, Zou, Sailan, Tang, Dongmei, Fan, Chen, Xie, Yongmei, Wei, Yuquan, Tian, Yan, Fu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480316/
https://www.ncbi.nlm.nih.gov/pubmed/30837196
http://dx.doi.org/10.1016/j.molmet.2019.02.003