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Perm1 regulates CaMKII activation and shapes skeletal muscle responses to endurance exercise training

OBJECTIVE: Endurance exercise training remodels skeletal muscle, leading to increased mitochondrial content and oxidative capacity. How exercise entrains skeletal muscle signaling pathways to induce adaptive responses remains unclear. In past studies, we identified Perm1 (PGC-1 and ERR induced regul...

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Detalles Bibliográficos
Autores principales: Cho, Yoshitake, Tachibana, Shizuko, Hazen, Bethany C., Moresco, James J., Yates, John R., Kok, Bernard, Saez, Enrique, Ross, Robert S., Russell, Aaron P., Kralli, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480336/
https://www.ncbi.nlm.nih.gov/pubmed/30862473
http://dx.doi.org/10.1016/j.molmet.2019.02.009