1,2,4-Oxadiazole/2-Imidazoline Hybrids: Multi-target-directed Compounds for the Treatment of Infectious Diseases and Cancer

Replacement of amide moiety with the 1,2,4-oxadiazole core in the scaffold of recently reported efflux pump inhibitors afforded a novel series of oxadiazole/2-imidazoline hybrids. The latter compounds exhibited promising antibacterial activity on both Gram-positive (Staphylococcus aureus, Bacillus s...

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Detalles Bibliográficos
Autores principales: Shetnev, Anton, Baykov, Sergey, Kalinin, Stanislav, Belova, Alexandra, Sharoyko, Vladimir, Rozhkov, Anton, Zelenkov, Lev, Tarasenko, Marina, Sadykov, Evgeny, Korsakov, Mikhail, Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480344/
https://www.ncbi.nlm.nih.gov/pubmed/30959765
http://dx.doi.org/10.3390/ijms20071699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480344/
https://www.ncbi.nlm.nih.gov/pubmed/30959765
http://dx.doi.org/10.3390/ijms20071699

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