Cargando…
Hydrophobic Amines and Their Guanidine Analogues Modulate Activation and Desensitization of ASIC3
Acid-sensing ion channel 3 (ASIC3) is an important member of the acid-sensing ion channels family, which is widely expressed in the peripheral nervous system and contributes to pain sensation. ASICs are targeted by various drugs and toxins. However, mechanisms and structural determinants of ligands’...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480424/ https://www.ncbi.nlm.nih.gov/pubmed/30959896 http://dx.doi.org/10.3390/ijms20071713 |