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Apoptosis Induction byHistone Deacetylase Inhibitors in Cancer Cells: Role of Ku70
Histone deacetylases (HDACs) are a group of enzymes that regulate gene transcription by controlling deacetylation of histones and non-histone proteins. Overexpression of HDACs is found in some types of tumors and predicts poor prognosis. Five HDAC inhibitors are approved for the treatment of cutaneo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480544/ https://www.ncbi.nlm.nih.gov/pubmed/30935057 http://dx.doi.org/10.3390/ijms20071601 |