Crude α-Mangostin Suppresses the Development of Atherosclerotic Lesions in Apoe-Deficient Mice by a Possible M2 Macrophage-Mediated Mechanism

Lifestyle choices play a significant role in the etiology of atherosclerosis. Male Apoe(−/−) mice that develop spontaneous atherosclerotic lesions were fed 0%, 0.3%, and 0.4% mangosteen extracts, composed largely of α-mangostin (MG), for 17 weeks. Body weight gains were significantly decreased in bo...

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Detalles Bibliográficos
Autores principales: Shibata, Masa-Aki, Harada-Shiba, Mariko, Shibata, Eiko, Tosa, Hideki, Matoba, Yoshinobu, Hamaoka, Hitomi, Iinuma, Munekazu, Kondo, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480575/
https://www.ncbi.nlm.nih.gov/pubmed/30959963
http://dx.doi.org/10.3390/ijms20071722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480575/
https://www.ncbi.nlm.nih.gov/pubmed/30959963
http://dx.doi.org/10.3390/ijms20071722

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