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3′-O-β-d-glucopyranosyl-α,4,2′,4′,6′-pentahydroxy-dihydrochalcone, from Bark of Eysenhardtia polystachya Prevents Diabetic Nephropathy via Inhibiting Protein Glycation in STZ-Nicotinamide Induced Diabetic Mice

Previous studies have shown that accumulation of advanced glycation end products (AGEs) can be the cause of diabetic nephropathy (DN) in diabetic patients. Dihydrochalcone 3′-O-β-d-glucopyranosyl α,4,2′,4′,6′-pentahydroxy–dihydrochalcone (1) is a powerful antiglycation compound previously isolated f...

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Detalles Bibliográficos
Autores principales: Pérez Gutierrez, Rosa Martha, García Campoy, Abraham Heriberto, Paredes Carrera, Silvia Patricia, Muñiz Ramirez, Alethia, Mota Flores, José Maria, Flores Valle, Sergio Odin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480600/
https://www.ncbi.nlm.nih.gov/pubmed/30925713
http://dx.doi.org/10.3390/molecules24071214