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Comprehensive kinome NGS targeted expression profiling by KING-REX

BACKGROUND: Protein kinases are enzymes controlling different cellular functions. Genetic alterations often result in kinase dysregulation, making kinases a very attractive class of druggable targets in several human diseases. Existing approved drugs still target a very limited portion of the human...

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Detalles Bibliográficos
Autores principales: Carapezza, Giovanni, Cusi, Carlo, Rizzo, Ettore, Raddrizzani, Laura, Di Bella, Sebastiano, Somaschini, Alessio, Leone, Antonella, Lupi, Rosita, Mutarelli, Margherita, Nigro, Vincenzo, di Bernardo, Diego, Magni, Paolo, Isacchi, Antonella, Bosotti, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480677/
https://www.ncbi.nlm.nih.gov/pubmed/31014245
http://dx.doi.org/10.1186/s12864-019-5676-3