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Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy

BACKGROUND: There are no accepted universal biomarkers capable to accurately predict response to immuno-checkpoint inhibitors (ICI). Although recent literature has been flooded with studies on ICI predictive biomarkers, available data show that currently approved companion diagnostics either leave o...

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Detalles Bibliográficos
Autores principales: Pallocca, Matteo, Angeli, Davide, Palombo, Fabio, Sperati, Francesca, Milella, Michele, Goeman, Frauke, De Nicola, Francesca, Fanciulli, Maurizio, Nisticò, Paola, Quintarelli, Concetta, Ciliberto, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480695/
https://www.ncbi.nlm.nih.gov/pubmed/31014354
http://dx.doi.org/10.1186/s12967-019-1865-8