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Downregulation of lncRNA CCAT1 enhances 5-fluorouracil sensitivity in human colon cancer cells

BACKGROUND: The purpose of this study was to determine the aberrant expression of the long noncoding RNA (lncRNA) colon cancer-associated transcript 1 (CCAT1) in 5-fluorouracil-resistant colonic neoplasm cells and to elucidate its effects on the 5-fluorouracil sensitivity of human colonic neoplasm c...

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Detalles Bibliográficos
Autores principales: Yang, Chun, Pan, Yong, Deng, Shao Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480879/
https://www.ncbi.nlm.nih.gov/pubmed/31039730
http://dx.doi.org/10.1186/s12860-019-0188-1