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A Viperin Mutant Bearing the K358R Substitution Lost its Anti-ZIKA Virus Activity

Interferon-induced viperin (VP) was identified as playing an important role in the innate immune response against Zika virus (ZIKV). The 361 amino acid long human VP protein comprises of a highly conserved C-terminal region, which has been associated with VP antiviral properties against ZIKV. In the...

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Detalles Bibliográficos
Autores principales: Vanwalscappel, Bénédicte, Gadea, Gilles, Desprès, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480927/
https://www.ncbi.nlm.nih.gov/pubmed/30934824
http://dx.doi.org/10.3390/ijms20071574