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A Viperin Mutant Bearing the K358R Substitution Lost its Anti-ZIKA Virus Activity
Interferon-induced viperin (VP) was identified as playing an important role in the innate immune response against Zika virus (ZIKV). The 361 amino acid long human VP protein comprises of a highly conserved C-terminal region, which has been associated with VP antiviral properties against ZIKV. In the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480927/ https://www.ncbi.nlm.nih.gov/pubmed/30934824 http://dx.doi.org/10.3390/ijms20071574 |