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Bone Marrow Endothelial Cells Influence Function and Phenotype of Hematopoietic Stem and Progenitor Cells after Mixed Neutron/Gamma Radiation

The bone marrow (BM) microenvironment plays a crucial role in the maintenance and regeneration of hematopoietic stem (HSC) and progenitor cells (HSPC). In particular, the vascular niche is responsible for regulating HSC maintenance, differentiation, and migration of cells in and out of the BM. Damag...

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Detalles Bibliográficos
Autores principales: Cary, Lynnette, Noutai, Daniel, Salber, Rudolph, Fadiyimu, Opeyemi, Gross, Arthur, Almeida-Porada, Graca, Kidane, Yared, Whitnall, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480930/
https://www.ncbi.nlm.nih.gov/pubmed/30978983
http://dx.doi.org/10.3390/ijms20071795