“Mirror” Method to Estimate Mutagenic Activity of DNA Lesions

We propose an improved method for detecting mutations that arise in DNA due to misincorporations of deoxyadenosine-5′-monophosphate (dAMP) opposite 7,8-dihydro-8-oxoguanine (8-oxoG). The method is based on the synthesis of complementary chains (“mirror” products) using a template containing 8-oxoG....

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Detalles Bibliográficos
Autores principales: Gening, Leonid V., Shevchenko, Oleg V., Kazachenko, Konstantin Y., Tarantul, Vyacheslav Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481070/
https://www.ncbi.nlm.nih.gov/pubmed/31164573
http://dx.doi.org/10.3390/mps1030032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481070/
https://www.ncbi.nlm.nih.gov/pubmed/31164573
http://dx.doi.org/10.3390/mps1030032

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