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Identification of Chinese Herbal Compounds with Potential as JAK3 Inhibitors

The Janus kinases (JAKs) consist of four similar tyrosine kinases and function as key hubs in the signaling pathways that are implicated in both innate and adaptive immunity. Among the four members, JAK3 is probably the more attractive target for treatment of inflammatory diseases because its inhibi...

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Detalles Bibliográficos
Autores principales: Su, Dan, Gao, Yu-Qiao, Deng, Yong-Jie, Zhang, Han-Hui, Wu, You-Ru, Hu, Ying, Mei, Quan-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481137/
https://www.ncbi.nlm.nih.gov/pubmed/31093295
http://dx.doi.org/10.1155/2019/4982062