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Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression

Autophagy may play a critical role in colon cancer stem cells (CCSCs)-related cancer development. Here, we investigate whether accumulation of infection/injury-induced CCSCs due to impaired autophagy influences colon cancer development and progression. When Apc(++) mice were infected with Citrobacte...

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Detalles Bibliográficos
Autores principales: Roy, Badal Chandra, Ahmed, Ishfaq, Ramalingam, Satish, Jala, Venkatakrishna, Haribabu, Bodduluri, Ramamoorthy, Prabhu, Ashcraft, John, Valentino, Joseph, Anant, Shrikant, Sampath, Venkatesh, Umar, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481322/
https://www.ncbi.nlm.nih.gov/pubmed/31040926
http://dx.doi.org/10.18632/oncotarget.26684