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The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting

BACKGROUND: Irinotecan use is limited due to severe toxicity. Preconditioning by fasting (PBF) protects against side effects of irinotecan while preserving its antitumor activity. The mechanisms underlying the effects of PBF still need to be elucidated. Here, we investigated the transcriptional resp...

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Detalles Bibliográficos
Autores principales: Jongbloed, Franny, Huisman, Sander A., van Steeg, Harry, Pennings, Jeroen L.A., IJzermans, Jan N.M., Dollé, Martijn E.T., de Bruin, Ron W.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481335/
https://www.ncbi.nlm.nih.gov/pubmed/31040913
http://dx.doi.org/10.18632/oncotarget.26776