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The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting
BACKGROUND: Irinotecan use is limited due to severe toxicity. Preconditioning by fasting (PBF) protects against side effects of irinotecan while preserving its antitumor activity. The mechanisms underlying the effects of PBF still need to be elucidated. Here, we investigated the transcriptional resp...
Autores principales: | Jongbloed, Franny, Huisman, Sander A., van Steeg, Harry, Pennings, Jeroen L.A., IJzermans, Jan N.M., Dollé, Martijn E.T., de Bruin, Ron W.F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481335/ https://www.ncbi.nlm.nih.gov/pubmed/31040913 http://dx.doi.org/10.18632/oncotarget.26776 |
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