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Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells

Vitamin K serves as an essential co-factor in the γ-carboxylation of glutamate to γ-carboxyglutamate (GLA), a post-translational modification mediated by gamma-glutamyl carboxylase (GGCX) and vitamin K oxidoreductases (VKORC1 or VKORC1L1). While both phylloquinone (K1) and menaquinone (K2) support t...

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Detalles Bibliográficos
Autores principales: Beaudin, Sarah, Kokabee, Leila, Welsh, JoEllen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481349/
https://www.ncbi.nlm.nih.gov/pubmed/31040920
http://dx.doi.org/10.18632/oncotarget.26765