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Inferring Causal Relationships Between Risk Factors and Outcomes from Genome-Wide Association Study Data
An observational correlation between a suspected risk factor and an outcome does not necessarily imply that interventions on levels of the risk factor will have a causal impact on the outcome (correlation is not causation). If genetic variants associated with the risk factor are also associated with...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481551/ https://www.ncbi.nlm.nih.gov/pubmed/29709202 http://dx.doi.org/10.1146/annurev-genom-083117-021731 |