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Inferring Causal Relationships Between Risk Factors and Outcomes from Genome-Wide Association Study Data

An observational correlation between a suspected risk factor and an outcome does not necessarily imply that interventions on levels of the risk factor will have a causal impact on the outcome (correlation is not causation). If genetic variants associated with the risk factor are also associated with...

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Detalles Bibliográficos
Autores principales: Burgess, Stephen, Foley, Christopher N., Zuber, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481551/
https://www.ncbi.nlm.nih.gov/pubmed/29709202
http://dx.doi.org/10.1146/annurev-genom-083117-021731