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Infection drives meningeal engraftment by inflammatory monocytes that impairs CNS immunity

Tissue macrophages have an embryonic origin and can be replenished in some tissues under steady state conditions by blood monocytes. However, little is known about the residency and properties of infiltrating monocytes after an inflammatory challenge. The meninges of the central nervous system (CNS)...

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Detalles Bibliográficos
Autores principales: Rua, Rejane, Lee, Jane Y., Silva, Alexander B., Swafford, Isabella S., Maric, Dragan, Johnson, Kory R., McGavern, Dorian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481670/
https://www.ncbi.nlm.nih.gov/pubmed/30886419
http://dx.doi.org/10.1038/s41590-019-0344-y