Sarcolipin Signaling Promotes Mitochondrial Biogenesis and Oxidative Metabolism in Skeletal Muscle

The major objective of this study was to understand the molecular basis of how sarcolipin uncoupling of SERCA regulates muscle oxidative metabolism. Using genetically engineered sarcolipin (SLN) mouse models and primary muscle cells, we demonstrate that SLN plays a crucial role in mitochondrial biog...

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Detalles Bibliográficos
Autores principales: Maurya, Santosh K., Herrera, Jose L., Sahoo, Sanjaya K., Reis, Felipe C.G., Vega, Rick B., Kelly, Daniel P., Periasamy, Muthu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481681/
https://www.ncbi.nlm.nih.gov/pubmed/30208317
http://dx.doi.org/10.1016/j.celrep.2018.08.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481681/
https://www.ncbi.nlm.nih.gov/pubmed/30208317
http://dx.doi.org/10.1016/j.celrep.2018.08.036

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