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Geometric confinement is required for recovery and maintenance of chondrocyte phenotype in alginate

Human articular chondrocytes lose their native phenotype when expanded in traditional monolayer cultures. As a consequence, hydrogel encapsulation has been investigated as a means to maintain the natural phenotype. Alginate has been widely used for cartilage engineering as it has been shown to enabl...

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Detalles Bibliográficos
Autores principales: Cooke, Megan E., Pearson, Mark J., Moakes, Richard J. A., Weston, Christopher J., Davis, Edward T., Jones, Simon W., Grover, Liam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481693/
https://www.ncbi.nlm.nih.gov/pubmed/31069284
http://dx.doi.org/10.1063/1.5006752