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Genotyping in the MHC locus: potential for defining predictive markers in sarcoidosis

In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-α is a central mediator of granuloma formation and since elevated TNF-α levels are found during active phases of sarcoidosis, genetic polymorphisms correlating w...

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Detalles Bibliográficos
Autores principales: Seitzer, Ulrike, Gerdes, Johannes, Müller-Quernheim, Joachim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64817/
https://www.ncbi.nlm.nih.gov/pubmed/11806841
http://dx.doi.org/10.1186/rr178